Here's some indication that Alzheimer's disease may
have causation from Chlamydia pneumoniae bacteria. I figured sooner
or later, they would find some type of bacterial or viral underpinning
(or both). Hopefully these findings will incite additional research
on this condition.
Bacteria Linked To Alzheimer's Disease
(HealthDayNews) -- There's a link between the common respiratory
bacteria Chlamydia pneumoniae and amyloid plaques found in the brains
of people with non-hereditary Alzheimer's disease.
That's the news from a study by researchers at the Philadelphia
College of Osteopathic Medicine's Center for the Study of Chronic
Diseases of Aging.
The research in mice appears in the April issue of the journal
Neurobiology of Aging.
The researchers have spent several years studying this link. This
new research builds on their previous finding that C. pneumoniae
is present in 90 percent of brains of people with Alzheimer's disease.
In this most recent study, the researchers showed that when the
bacteria was sprayed into the noses of mice that are not predisposed
to amyloid plaques, it caused progressive deposition of amyloid
plaques, creating a partial model of Alzheimer's disease.
"We believe this could be a trigger mechanism for the pathology
in Alzheimer's disease," lead researcher Brian Balin says in
a prepared statement.
"People have been suspecting this for decades but could
not find anything. It is very difficult to pinpoint an infectious
cause for a progressive, chronic disease. We also believe that our
isolation of Chlamydia pneumoniae from the human Alzheimer's diseased
brain and induction of pathology in normal mice is proof of principle
that this can be a causative mechanism turning on pathology,"
U.S. National Institute on Aging has more about Alzheimer's disease.
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